I couldn't let the end of year pass without popping back on here to wish anyone who still receives notifications of new posts, a very happy New Year. I hope ... The post Here's to a Happy New Year appeared first on A Makeup & Beauty Blog - ...

 

Lipglossiping - Here’s to a Happy New Year




Here’s to a Happy New Year

I couldn’t let the end of year pass without popping back on here to wish anyone who still receives notifications of new posts, a very happy New Year. I hope that, whether good or bad, you are able to draw a line under 2015 and welcome the New Year later this evening with open arms and a certain degree of optimism.

For me, 2015 has felt a little like a missed opportunity. It hasn’t been a bad year but I’ve not made the most of it and with hindsight, that’s something I don’t want to repeat in 2016. I’m not one of life’s natural go-getters. I hold myself back from opportunities both with caution and a lack of confidence in my ability to achieve, creating the perfect self-fulfilling prophecy that I happily use as a justification for shrugging off the next opportunity. Basically, I’m a bit of a pussy and somewhat lazy, combine the two and you’ve got a perfect storm.

But it hasn’t been all doom and gloom!

My little family are happy and healthy, I finally have a sofa that can fit more than two bottoms (seriously, this is a big deal for me!), we haven’t overspent this year so can hopefully get through the first part of next year without any sleepless nights, I’ve had the opportunity for many lovely chats with my sister and spent lots more time with my brother. I’ve loved watching my children enjoy life, developing the quirks that make them them, and taking such pleasure from learning. I’ve even become semi-competent at playing the ukulele!

In 2016, I just hope for good health for us all. The rest of it, as I have come to appreciate this year, can be greatly improved by a positive mental attitude.

Happy New Year chaps, onwards and upwards. x

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23andMe DNA Testing in the UK – My Results #23andme #dnatesting

When I received the email from 23andMe informing me that my results were ready, the rush of excitement, anticipation, and fear was real. I could taste it. My heart rate quickened and I had to steady myself before clicking through. You see, these things are no joke. If you’d rather hide under the metaphorical duvet covers and not face up to the potential realities of your future, this service probably isn’t for you. Thoughts of Parkinsons, Alzheimers, Breast Cancer and other inherited conditions could well be about to take a goose-step into your psyche.

For me, although the idea of discovering potential health issues wasn’t entirely unproblematic, I felt that I’d rather be forewarned. There are so many lifestyle changes that I could make, that I should make to boost my chances of a healthier later-life and I’m not opposed to the idea of a little kick up the bum.

Of course, one should not lose sight of two very important facts.

Just because your genes show a disposition to developing a certain condition, this does not mean that you will inherit. And perhaps more importantly, just because your genes don’t show a disposition… doesn’t mean that you won’t develop it anyway. I may not show any mutations in the BRCA1/BRCA2 gene varients, but that doesn’t make me immune to developing breast or ovarian cancer, I will still be vigilant in my monthly boob checks – I just won’t be rushing off to my GP demanding that he lop both breasts off there and then. Clearly, I’m not the type to overreact!

So caveats aside… what did my results show?

I’m at a higher risk of developing Alzheimers thanks to having one copy of the APOE ε3 variant and one copy of the ε4 variant. The ε4 variant is particularly associated with higher risk for developing Alzheimer’s disease. Infact, it’s the strongest known hereditary risk factor for late-onset Alzheimer’s (after the age of 65). But as frightening as this may initially sound, it puts me in a category shared by roughly 22% of people with European ancestry. Mate, I’m not alone – and when you consider the rising incidence of Alzheimers in an aging population, I’m not especially horrified. As I’ve said before, both my mother and my grandmother have suffered the disease, I pretty much expected this result.

But what’s the point of receiving this information if you’re not going to do anything about it? What can you do to prevent Alzheimers? Well, for me… it will just mean that I’m more mindful about trying to keep my blood pressure low, reducing my risks of diabetes, and taking an omega-3 supplement. I’m not going to lose sleep over it, truly. But you will catch me looking up from whatever I’m doing when they talk about new research in battling the disease on the news.

My genes also show that I also have Inherited Thrombophilia, something that I wasn’t aware of but basically means that I have a higher risk of DVT (deep vein thrombosis) and PE (pulmonary embolism). To be more specific, I have one copy of the Factor V Leiden variant in the F5 gene. Having this variant is associated with about five times higher odds of developing abnormal blood clots in people with European ancestry.

Now, how is that not useful to know? It means I won’t be taking any risks on long-haul flights, if I have to have surgery or my leg put in a cast, you can be sure I’ll be telling my care providers about this possible complication to give them the option of treating me with blood thinners. I mean, seriously, how could being forearmed with this knowledge not be a good thing?

Now, in terms of the “scary” stuff that 23andMe test for, this is my lot (thankfully).

I don’t have any increased genetic risk for Parkinsons or BRCA1/2-related breast cancers, and there are numerous other serious but lesser-known conditions shown within my 23andMe control panel, all of which I show only a typical (rather than increased) risk of developing.

My control panel also shows that my body metabolizes certain proton pump inhibitors (anti-acids such as omeprazole/lansoprazole) faster than the typical response. This is of interest to me as I am allergic to NSAIDs (aspirin/ibuprofen) and have been treated on numerous occasions for stomach ulcers. On a basic level it means that I may need a higher dosage of these drugs than usual to have an effect. So far, I’m generally ok with what the doctor prescribes… but it’s good to know that if I don’t respond well to the usual treatment in the future, there could be a reason for it.

The serious stuff now out of the way, the rest is a bit of fun and frippery, I’ll run through a quick facts-about-me-determined-from-my-genes list so you can get an idea of the kind of things that 23andMe tell you about.

•  I do not flush in response to alcohol. (just in response to the stupid things I say whilst under its effects!)

•  I am “taste-blind” to the bitter components found in cabbage, raw broccoli, coffee, tonic water, and dark beers.

•  My ear-wax type is err, “wet”. Who knew earwax was highly heritable?! Also, women with a wet earwax type are likely to produce more colostrum when breastfeeding!

•  Interestingly and incorrectly, my eye colour is likely to be brown. My Dad’s eyes are brown and my Mum’s blue… brown is dominant, so I guess that’s the basis of the assumption? Mine are green, which means that with my particular inherited genotype, I only had a 37% chance of getting green eyes.

•  I’m likely to be tolerant of lactose because I produce higher lactase enzyme levels.

•  I’m more likely to be a sprinter (as opposed to a marathon runner).

•  I’m unfortunately, not resistant to the most common strain of norovirus.

•  I’m a red hair “carrier” but am unlikely to have red hair myself. Put me with another red hair “carrier” and we could have the most beautiful flame-haired children.

•  I have moderately higher odds of detecting the scent of asparagus in my urine(!)

•  I’m likely to have more freckling than average

•  I metabolize caffeine quickly, reducing my chances of a coffee-induced heart attack

•  I have higher-than-average odds of disliking the taste of cilantro (coriander). I’m not bothered by it.

 

There are many more tidbits of useless info like this gathered from your DNA data. I can’t deny, It’s ridiculously good fun to read about yourself like this.

All of the above comes under the “Health” heading on the website, there’s a whole other section devoted to “Ancestry”.

I won’t go into too much details on this section (because I’ve already written too much!) except to say that my genetic data has revealed that I’m 99.9% Northern European and 0.1% West African. From that giant 99.9%, 78.% is British/Irish and 6.8% is French/German.

My mitochondrial DNA shows that I descend from maternal Haplogroup V, which originated in Iberia during the Ice Age. Apparently, Haplogroup V was likely common in “Doggerland”, an ancient land now drowned beneath the North Sea. Blimey!   This Haplogroup can now be found in 12% of people in the Basque region and 40% of Laplanders! I share my Haplogroup with Benjamin Franklin and err, Bono.  Nevermind, you can’t win ’em all.

So, once you’ve read your results… then what?  Well, things could actually get even more interesting in the future.  23andMe give you access to download your raw data and with this, you can upload the information to other 3rd-party websites.  These websites, such as Promethease and GEDMatch, will give you access to even more information based on your human genome data.  As you might imagine, these websites and databases are being constantly updated.  Your raw data has an extremely long shelf-life when it comes to usability.

I’ve written far too much but I’ll leave you with one last little tidbit of useless info.

An estimated 2.9% of my DNA is from Neanderthals, this puts me in the 87th percentile amongst other Europeans. I’m basically a knuckle-dragging, low-browed imbecile and it’s a miracle I’m not typing this with my feet.

If you’re interested in unlocking the mysteries of your DNA, I purchased my DNA kit directly from the 23andMe website but I believe you can also buy them from some Superdrug stores, they’re priced at £125 and results take around 6 weeks to process.

* this post contains affiliate links

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23andMe DNA Testing in the UK – My experiences (pre-results)

Ever wondered if your uncle’s cousin’s brother was, infact, your husband?  No, me neither… but I’m sure it happens in some places, like Yeovil or Darlington.  Anyway, despite society’s thirst for new technologies, I soon discovered that many people view DNA testing with the same kind of suspicion they reserve for tarot reading or “Psychic Sally”.  I’m not talking about the kind of DNA testing that proves X murdered Y at the Old Bailey, that kind of science is beyond reproach – I’m talking about the kind of DNA profiling that you and I can have done.  On ourselves.  Of course, it’s basically the same thing – but try telling that to some people. SOME PEOPLE.

To be fair, my prior knowledge of DNA testing was pretty sketchy, it was based around everything I’ve ever learnt from watching The Jeremy Kyle Show, which, as I’m sure you can imagine… amounts to not an awful lot.

If I’m being honest, vanity had a lot to do with my decision to have my DNA profiled.  I mean, we all know that the best subject in the world to talk about is ourselves.  On the health side of things, I was curious to discover whether my DNA would show a genetic disposition toward Alzheimers now that both my mother and my paternal grandmother had been diagnosed with the disease.  I also wanted to find out about any other genetic risk factors, including the much talked about BRCA1 and BRCA2 mutations that can significantly increase the risk of female breast and ovarian cancers.

23andme offers a wealth of health-related information (note, the FDA do not allow the company to provide health-related information on the basis of its genome scan in the US) to many of its customers but if looking into a potentially rather murky crystal ball doesn’t float your boat, perhaps the ancestry side of things is more to your taste.  The results offer a full breakdown of your ancestral composition, detailing what parts of the world your ancestry hails from, whether you have any famous relatives, and just how much of your DNA is basically Neanderthal.  It will inform you of any relatives it discovers from across its network of customers, providing of course, you grant permission for it to perform that kind of private “matchmaking”.

So, your appetite is whetted.  How does all this magic happen?

I signed up and paid my monies on the 23andme website… it’s not cheap by the way, it’ll set you back £125 – but I saw that as a bit of a bargain after I’d done some research into getting my BRCA1/BRCA2 genes tested privately at a cost of upwards of £1000.

Once signed up, you sit back and wait.  And the waiting is the dullest part of the whole procedure.  While 23andme offer their services within the UK, they’re not based here and it took just over a fortnight before I received my DNA Collection Kit.

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The process involves depositing saliva into a collection tube.  It’s basically a spit-kit, pure and simple.  I’ve never felt more feral, or indeed impressed by my gobbing abilities.  It took me far less time to fill to the line than I thought it would, I was probably thinking about steak and chips… I usually am.  Once your “deposit” is safely sealed in the box provided, you’ll need to head for your nearest post office, feeling like a dirty miscreant handing over bodily fluids to an unsuspecting Royal Mail employee.

AND THEN YOU WAIT.

It took a painstakingly long six weeks before I received my results.  I felt a rush of excitement, anticipation, and dare I say it, fear when that email pinged its way into my inbox.

But more of that next time…

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Burts Bees Intense Hydration Treatment Mask

We all know that prevention is better than cure. Many years later, I can still recall the disapproving looks I would receive from my doctor when he asked me how regularly I was taking my preventer inhaler.  You see, being the know-it-all thirteen year old that I was, I felt that I was handling my asthma pretty well using only my blue inhaler.  That was, until I was told that taking the reliever inhaler 6 times a day does not equal a controlled condition.

The same goes for problem skin.

But clearly, I am still very much thirteen years old at heart because here I am, about to extol the “daily use” virtues of something that feels very much like a “cure” product.  I should probably just count my blessings that I don’t spend all my money in Our Price nowadays.

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Burts Bees Intense Hydration Treatment Mask is a luxuriously thick cream that spreads beautifully and deeply nourishes the upper layers of skin.  The particular benefits of this product, for me, is its unique combination of ingredients that provide a great-feeling as well as effective moisturising product.

It’s as though the chemists have struck a perfect balance for my skin and personal tastes.  Although rich in glycerin, which works as a great (albeit inexpensive) humectant, keeping water bound within these upper layers of skin, the texture lacks the tackiness that often comes with glycerin-based products.  In addition to this, it boasts instant emollient benefits as a skin smoother, feeling comfortably nourishing on the face without being overly heavy.

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The mask spreads nicely, leaving behind a white sheen that over the course of a minute or two, dissipates, taking any feelings of post-cleansing tightness with it.

My only caveat with the Intense Hydration Mask is its over-reliance on fragrance.  As with many other Burts Bees products, this one is also highly-scented.  Thankfully, my skin tolerates perfume in skincare very well, but I know that many do not and it’s a shame that a brand which is often so beneficial to people with dry and sensitive skin, feels the need to use potential irritants so aggressively in its products.  This one, especially.

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My opening paragraph may have alerted you to the fact that instead of using this product as a “treatment mask”, I mostly use it as a daily moisturiser… tailoring the amount I apply to the ever-changing demands of my skin.  I only need to use a very small quantity, pea-sized, most days… meaning that this 110g tube is going to last me a very long time.  Once a week, after applying a clay-based mask across my t-zone, I apply a slightly thicker layer before bed.

I do love mini-miracle products, those ones that make tangible differences to your skin after only one use.  Ain’t no-one got time to wait 12-weeks for results and this one is, for me at least, a bonafide beauty saviour.

Burts Bees Intense Hydration Treatment Mask is available to buy online from feelunique.com priced at £17.95

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Review: The Balmer Lawn Hotel, New Forest

My husband had only one simple request for his recent 40th birthday.  Unfortunately, I couldn’t gift him with eternal youth, so instead I opted for a good night’s sleep.  As a light sleeper (I sleep like the dead), it’s fair to say that poor Pauly’s shut-eye has been momentously disrupted ever since the arrival of baby Joe.  Every snuffle, snort, and baby-fart permanently recorded in the under eye circles that adorn his face.

Of course, I wasn’t just going to take him to any old hotel.  Oh no, I made that mistake last time.  And if you remember that less-than-favourable review, you might remember that I mentioned another hotel that I had wanted to secure but had been unable due to  incompatible dates.  Long story short, I had no such problem this time and promptly booked us both in for an overnight stay at the Balmer Lawn Hotel in the New Forest.

This time, I pounced upon a Travelzoo deal to procure our night of hopeful bliss.  I paid for an overnight stay with breakfast, two spa treatments and a three-course meal and awaited the treat with glee.

The day didn’t get off to a great start as I had to cancel the pre-booked spa treatments due to a last-minute offer of a hospital appointment that couldn’t be turned down.  However once that was out of the way, we dashed up the M27 and into the more serene surroundings of the New Forest.

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The Balmer Lawn is a hotel that I must have driven past a thousand times, I think that’s why I’ve wanted to stay for so long… the old hunting lodge has an imposing charm, set alone in splendid surroundings and I’ve always wondered what it’s like inside.  Sadly, I didn’t get to experience its full charms as the hotel was slap-bang in the middle of refurbishment works when we arrived and the main lounge area, with its roaring open fire, was sadly sealed off behind sheets and boards!

It couldn’t be helped though, and despite our room being fairly close to the hub of the work, we weren’t disturbed by any noise during sleeping hours.  I look forward to seeing the result of the work in the future.

We arrived a little earlier than I’d anticipated but it was no problem at all for the receptionist who took it in her stride and cheerfully checked us in early.  I should point out at this point that The Balmer Lawn website has the rather nifty “Look Before You Book” feature which offers plentiful photos of all the rooms available!

We’d only paid for a standard room as part of the deal but the hotel has a policy of upgrading all guests whenever possible, so we ended up with a lovely four poster, superior room with forest views.  Room 7, infact… take a look for yourself.  It was spacious and included everything you’d need for a comfortable overnight stay.

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Once settled in the room, we decided to make best use of our child-free time by checking out the leisure facilities.  As previously mentioned, we had to forfeit our spa treatments (through no fault of the hotel) but we weren’t going to let it spoil our fun and headed straight downstairs to the pool area which was blissfully deserted.  The jacuzzi was heavenly, and I parked myself in its hot, bubbling waters, deciding there and then that I was going to exercise squatters rights until at least May.

I may well have followed through with my dastardly plan had I not realised that it was almost dinner time, and if there’s one thing that can get my backside moving, it’s the promise of food. Slipping back to our room, I took the opportunity to catch up on some TV and refresh my makeup before heading down to the dining room where our attentive (but not too attentive) waiter was ready to talk us through the menu.

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Sadly, the dining room was too dark to do the food much justice in my photos but from a sweetcorn chowder with cornbread to duck and soft boiled egg for starters, a venison and kale main to a trio of beef with vegetable crisps, we both completed the delicious proceedings with a treacle tart.

The food couldn’t be faulted on both presentation and taste, nouvelle cuisine done beautifully, but we left the table with room for a little more and thankful for the full three courses.

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There was just enough time for a relaxing soak in the tub before we made our selections for an in-room breakfast order (£5 tray charge, well worth it) and retired for the night.  The bed was extremely comfortable but I must admit that the best bit of all was the blissful silence and completely undisturbed night of sleep that we both cherished.

Waking the next morning, we enjoyed a full English breakfast sat at the table in our room, overlooking the beauty of the local surroundings before taking full advantage of a late 2pm check out by taking our lazy selves straight back to bed to stock up on some more zzzzzz’s before the return to reality.

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When we booked our night away, we were in desperate need of a recharge, both physically and emotionally.  The kindness of the staff throughout the hotel is what shone through, nothing felt like too much trouble and everyone we passed greeted us with a warm smile and a friendly “hello”.  The people who work at this establishment should be treasured because they helped facilitate the R&R that we so desired, expertly.

Sadly, that was back in early January and we’re already feeling the itch for another recharge!

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