| Paul Arciero, Ph. D. , FACSM, FTOS from Isagenix® International on Vimeo. Trainer: Paul Arciero, Ph. D. , FACSM, FTOS If you are familiar with Isagenix, you have likely heard of some of the impressive research and published papers Dr. Paul Arciero ...
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Isagenix Health

Get to Know Dr. Paul Arciero

 

Get to Know Dr. Paul Arciero | Paul Arciero, Ph.D., FACSM, FTOS from Isagenix® International on Vimeo.

Trainer: Paul Arciero, Ph.D., FACSM, FTOS

If you are familiar with Isagenix, you have likely heard of some of the impressive research and published papers Dr. Paul Arciero and his team have accomplished and contributed to. Get to know the man behind the research, from how he found his passion in health and fitness to his favorite Isagenix products.

For an audio-only version of this podcast, use the player below:

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Support for Coming Off Medicated Weight Loss

 

Coming Off Medicated Weight Loss Support from Isagenix® International on Vimeo.

Trainer: Joshua Plant, Ph.D., Chief Science Officer

Many individuals who are using one of the popular pharmaceuticals to support weight loss fear the bounce back that may come when they eventually come off these medications. Dr. Plant explains how Isagenix is the perfect partner for these individuals to help maintain their weight loss and continue to support their weight management goals long term. From our supportive community, to the scientifically validated combination of Shake Days and Cleanse Days- Isagenix is here to help.

For an audio-only version of this podcast, use the player below:

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Support on Medicated Weight Loss

 

Support On Medicated Weight Loss with Dr. Plant part 2 from Isagenix® International on Vimeo.

Trainer: Joshua Plant, Ph.D., Chief Science Officer

If you are using one of the popular medications to support weight loss, Isagenix is here to help. Dr. Plant explains how you can optimize your weight loss journey with the help of targeted nutritional support to help maintain muscle, support metabolic health, and increase nutrient density in your diet. Don’t just lose weight, lose the right kind of weight to keep it off and feel your best long term.

For an audio-only version of this podcast, use the player below:

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Seeking an Alternative to Medicated Weight Loss with Dr. Plant

 

Trainer: Joshua Plant, Ph.D., Chief Science Officer

There are so many medications on the market promising the ultimate solution to weight loss. Listen in as Dr. Plant discusses medicated weight loss, the actual stats for those using these pharmaceuticals, and how Isagenix classic 30-Day Reset compares. If you are wondering if one of these medications might be the only solution for your weight management woes, this episode is for you.

For an audio-only version of this podcast, use the player below:

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GLP-1 Medications Negatively Impact Muscle Maintenance

GLP-1 (glucagon-like protein-1) receptor agonists like Wegovy and Ozempic are so popular that their use by an increasing number of Americans desiring their weight loss benefits is leading to shortages and increasing reports of “fake” drugs in the marketplace. These are doubly troublesome for those for whom the medications were initially developed—individuals with type 2 diabetes.

But did you know that despite their popularity and success in promoting weight loss, much of this loss is not just from body fat but also muscle?

Clinical studies have reported that 25-40% of total body weight loss is attributable to muscle loss. Indeed, rapid weight loss with these drugs may decrease your metabolic rate while reducing bone density.

Therefore, when considering these medications for weight loss, the goal should not simply be a reduction in overall weight but also an improvement in body composition with maintenance of your muscle mass. Without preventing muscle loss, the individual may exhibit what has frequently been called “skinny fat.” Being skinny fat may also negatively affect one’s quality of life and energy levels. So, having a lower body weight (even considered “ideal”) does not equate to being healthy.

Benefits of Maintaining Muscle Mass

Skeletal muscle is the largest organ in the human body and accounts for approximately 30-35% of an individual’s total weight. Muscles allow for body movement and provide many physiological functions within the body, not the least being their enrichment in mitochondria (the “battery” of life).  The benefits of maintaining muscle mass on overall health and wellness have been noted by many researchers (1). Indeed, having more muscle supports weight loss and maintenance since these tissues are the primary users of the body’s energy (as a result of all those mitochondria). This energy “burning” is even true during rest; when a person loses muscle mass, the resting metabolic rate decreases, too.

Luckily, there are lifestyle and dietary choices that can mitigate lean mass loss during weight loss. Moreover, individuals older than 60 are already more prone to muscle loss and need to be particularly mindful of building muscle and the potential muscle loss effects of GLP-1 medications.

High-Quality Dietary Protein Intake is Essential for Optimal Muscle Status

The dynamic relationship between muscle protein synthesis (MPS) and muscle protein breakdown (MPB) regulates total body muscle mass. Following a meal rich in protein (20-40g), MPS increases ∼2–3 fold, while MPB can be inhibited by ∼50% in young, healthy muscle; however, as noted previously, these effects are further blunted in older individuals and, likely, in those using GLP-1 drugs. Combining high-quality protein intakes spaced throughout the day with exercise (particularly resistance exercise) will reduce MPS and allow for the maintenance of muscular tone. In this context, high-quality proteins are also rich in essential amino acids required for MPS and its signaling to begin synthesis (with the protein’s leucine content being the most important amino acid).

In conclusion, the use of GLP-1 medications has been shown to promote rapid weight loss; however, much of that weight loss is attributed to the loss of muscle mass. By consuming high-quality protein meals or supplements evenly spaced throughout the day, combined with an exercise program, you can minimize the potentially harmful health effects of GLP-1-induced muscle loss.

References:

  1. Deutz NE, Bauer JM, Barazzoni R, et al. Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN expert group. Clin Nutr. 2014;33(6):929-936. doi:10.1016/j. clnu.2014.04.007

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